BDBM50387301 CHEMBL2048859

SMILES: CN(C)C1CCN(C1)c1ccccc1C=C1SC(O)=NC1=O

InChI Key: InChIKey=PRQMWOGCLLGXFR-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50387301   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50387301 (CHEMBL2048859) Show SMILES CN(C)C1CCN(C1)c1ccccc1C=C1SC(O)=NC1=O |w:14.15,c:20| Show InChI InChI=1S/C16H19N3O2S/c1-18(2)12-7-8-19(10-12)13-6-4-3-5-11(13)9-14-15(20)17-16(21)22-14/h3-6,9,12H,7-8,10H2,1-2H3,(H,17,20,21)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM1 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50387301 (CHEMBL2048859) Show SMILES CN(C)C1CCN(C1)c1ccccc1C=C1SC(O)=NC1=O |w:14.15,c:20| Show InChI InChI=1S/C16H19N3O2S/c1-18(2)12-7-8-19(10-12)13-6-4-3-5-11(13)9-14-15(20)17-16(21)22-14/h3-6,9,12H,7-8,10H2,1-2H3,(H,17,20,21)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM3 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50387301 (CHEMBL2048859) Show SMILES CN(C)C1CCN(C1)c1ccccc1C=C1SC(O)=NC1=O |w:14.15,c:20| Show InChI InChI=1S/C16H19N3O2S/c1-18(2)12-7-8-19(10-12)13-6-4-3-5-11(13)9-14-15(20)17-16(21)22-14/h3-6,9,12H,7-8,10H2,1-2H3,(H,17,20,21)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human PIM2 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATP				Bioorg Med Chem Lett 22: 4599-604 (2012) Article DOI: 10.1016/j.bmcl.2012.05.098 BindingDB Entry DOI: 10.7270/Q2348MDS
					More data for this Ligand-Target Pair