BDBM50387453 CHEMBL2047471

SMILES: CNC1CN(C1)C(=O)c1cc2cc(Cl)cc(F)c2[nH]1

InChI Key: InChIKey=ZSKPBGNERYGHMM-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387453   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50387453 (CHEMBL2047471) Show SMILES CNC1CN(C1)C(=O)c1cc2cc(Cl)cc(F)c2[nH]1 Show InChI InChI=1S/C13H13ClFN3O/c1-16-9-5-18(6-9)13(19)11-3-7-2-8(14)4-10(15)12(7)17-11/h2-4,9,16-17H,5-6H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim RCV GmbH& Co KG Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells				Eur J Med Chem 54: 660-8 (2012) Article DOI: 10.1016/j.ejmech.2012.06.016 BindingDB Entry DOI: 10.7270/Q2251K7H
					More data for this Ligand-Target Pair