BDBM50387664 CHEMBL2057766

SMILES: Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCC[C@H]3C(=O)Nc3ccccc3F)ccc2c1

InChI Key: InChIKey=SODXMFCMLOOZQF-SKVJQKLOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387664   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50387664 (CHEMBL2057766) Show SMILES Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)N3CCC[C@H]3C(=O)Nc3ccccc3F)ccc2c1 |r,TLB:7:8:14.15.13:10.11,16:14:8:10.11| Show InChI InChI=1S/C30H32F2N4O2/c31-22-10-9-20-14-19(7-8-21(20)15-22)18-36-24-11-12-25(36)17-23(16-24)33-30(38)35-13-3-6-28(35)29(37)34-27-5-2-1-4-26(27)32/h1-2,4-5,7-10,14-15,23-25,28H,3,6,11-13,16-18H2,(H,33,38)(H,34,37)/t24-,25-,28+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR3				Bioorg Med Chem Lett 22: 4951-4 (2012) Article DOI: 10.1016/j.bmcl.2012.06.042 BindingDB Entry DOI: 10.7270/Q2057H06
					More data for this Ligand-Target Pair