BDBM50387666 CHEMBL2058072

SMILES: COc1ccccc1NC(=O)[C@@H]1CCCN1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccc2cc(F)ccc2c1

InChI Key: InChIKey=QNOTUWLYCQMBHP-GTNKKZTPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387666   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50387666 (CHEMBL2058072) Show SMILES COc1ccccc1NC(=O)[C@@H]1CCCN1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccc2cc(F)ccc2c1 |r,TLB:27:26:19.20.25:22.23,THB:18:19:26:22.23| Show InChI InChI=1S/C31H35FN4O3/c1-39-29-7-3-2-5-27(29)34-30(37)28-6-4-14-35(28)31(38)33-24-17-25-12-13-26(18-24)36(25)19-20-8-9-22-16-23(32)11-10-21(22)15-20/h2-3,5,7-11,15-16,24-26,28H,4,6,12-14,17-19H2,1H3,(H,33,38)(H,34,37)/t25-,26-,28+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR3				Bioorg Med Chem Lett 22: 4951-4 (2012) Article DOI: 10.1016/j.bmcl.2012.06.042 BindingDB Entry DOI: 10.7270/Q2057H06
					More data for this Ligand-Target Pair