BDBM50387734 CHEMBL2058886

SMILES: NC(=N)SCc1cccc2c1oc1c(CSC(N)=N)cc(F)cc21

InChI Key: InChIKey=QBCGOAKVJHROLO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387734   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Natural resistance-associated macrophage protein 1 (Homo sapiens (Human))	BDBM50387734 (CHEMBL2058886) Show SMILES NC(=N)SCc1cccc2c1oc1c(CSC(N)=N)cc(F)cc21 Show InChI InChI=1S/C16H15FN4OS2/c17-10-4-9(7-24-16(20)21)14-12(5-10)11-3-1-2-8(13(11)22-14)6-23-15(18)19/h1-5H,6-7H2,(H3,18,19)(H3,20,21)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of NRAMP1 expressed in CHO cells				Bioorg Med Chem Lett 22: 5108-13 (2012) Article DOI: 10.1016/j.bmcl.2012.05.129 BindingDB Entry DOI: 10.7270/Q2QN67TM
					More data for this Ligand-Target Pair