BDBM50387737 CHEMBL2058889

SMILES: NC(=N)SCc1c(F)ccc2c1oc1c(CSC(N)=N)c(F)ccc21

InChI Key: InChIKey=MISHERGCFFUFGK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387737   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Natural resistance-associated macrophage protein 1 (Homo sapiens (Human))	BDBM50387737 (CHEMBL2058889) Show SMILES NC(=N)SCc1c(F)ccc2c1oc1c(CSC(N)=N)c(F)ccc21 Show InChI InChI=1S/C16H14F2N4OS2/c17-11-3-1-7-8-2-4-12(18)10(6-25-16(21)22)14(8)23-13(7)9(11)5-24-15(19)20/h1-4H,5-6H2,(H3,19,20)(H3,21,22)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of NRAMP1 expressed in CHO cells				Bioorg Med Chem Lett 22: 5108-13 (2012) Article DOI: 10.1016/j.bmcl.2012.05.129 BindingDB Entry DOI: 10.7270/Q2QN67TM
					More data for this Ligand-Target Pair