BDBM50387771 CHEMBL2057767

SMILES: Clc1nccc2c(cccc12)S(=O)(=O)N1CC(C1)C(=O)N1CCN(CC1)c1ccncc1

InChI Key: InChIKey=YKOABICJHYALBV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50387771   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50387771 (CHEMBL2057767) Show SMILES Clc1nccc2c(cccc12)S(=O)(=O)N1CC(C1)C(=O)N1CCN(CC1)c1ccncc1 Show InChI InChI=1S/C22H22ClN5O3S/c23-21-19-2-1-3-20(18(19)6-9-25-21)32(30,31)28-14-16(15-28)22(29)27-12-10-26(11-13-27)17-4-7-24-8-5-17/h1-9,16H,10-15H2	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	741	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by fl...				Bioorg Med Chem Lett 22: 5035-40 (2012) Article DOI: 10.1016/j.bmcl.2012.06.018 BindingDB Entry DOI: 10.7270/Q2KW5H39
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50387771 (CHEMBL2057767) Show SMILES Clc1nccc2c(cccc12)S(=O)(=O)N1CC(C1)C(=O)N1CCN(CC1)c1ccncc1 Show InChI InChI=1S/C22H22ClN5O3S/c23-21-19-2-1-3-20(18(19)6-9-25-21)32(30,31)28-14-16(15-28)22(29)27-12-10-26(11-13-27)17-4-7-24-8-5-17/h1-9,16H,10-15H2	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by fl...				Bioorg Med Chem Lett 22: 5035-40 (2012) Article DOI: 10.1016/j.bmcl.2012.06.018 BindingDB Entry DOI: 10.7270/Q2KW5H39
					More data for this Ligand-Target Pair