BDBM50387776 CHEMBL2057771

SMILES: O=C(C1CN(C1)S(=O)(=O)c1cccc2cnccc12)N1CCN(CC1)c1ccncn1

InChI Key: InChIKey=SENACPRMGTWPOB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50387776   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50387776 (CHEMBL2057771) Show SMILES O=C(C1CN(C1)S(=O)(=O)c1cccc2cnccc12)N1CCN(CC1)c1ccncn1 Show InChI InChI=1S/C21H22N6O3S/c28-21(26-10-8-25(9-11-26)20-5-7-23-15-24-20)17-13-27(14-17)31(29,30)19-3-1-2-16-12-22-6-4-18(16)19/h1-7,12,15,17H,8-11,13-14H2	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by fl...				Bioorg Med Chem Lett 22: 5035-40 (2012) Article DOI: 10.1016/j.bmcl.2012.06.018 BindingDB Entry DOI: 10.7270/Q2KW5H39
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50387776 (CHEMBL2057771) Show SMILES O=C(C1CN(C1)S(=O)(=O)c1cccc2cnccc12)N1CCN(CC1)c1ccncn1 Show InChI InChI=1S/C21H22N6O3S/c28-21(26-10-8-25(9-11-26)20-5-7-23-15-24-20)17-13-27(14-17)31(29,30)19-3-1-2-16-12-22-6-4-18(16)19/h1-7,12,15,17H,8-11,13-14H2	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by fl...				Bioorg Med Chem Lett 22: 5035-40 (2012) Article DOI: 10.1016/j.bmcl.2012.06.018 BindingDB Entry DOI: 10.7270/Q2KW5H39
					More data for this Ligand-Target Pair