BDBM50387782 CHEMBL2057497

SMILES: O=C(C1CN(C1)S(=O)(=O)c1cccc2ncccc12)N1CCN(CC1)c1ccncc1

InChI Key: InChIKey=GLJRUHNTCQSZIO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50387782   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50387782 (CHEMBL2057497) Show SMILES O=C(C1CN(C1)S(=O)(=O)c1cccc2ncccc12)N1CCN(CC1)c1ccncc1 Show InChI InChI=1S/C22H23N5O3S/c28-22(26-13-11-25(12-14-26)18-6-9-23-10-7-18)17-15-27(16-17)31(29,30)21-5-1-4-20-19(21)3-2-8-24-20/h1-10,17H,11-16H2	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by fl...				Bioorg Med Chem Lett 22: 5035-40 (2012) Article DOI: 10.1016/j.bmcl.2012.06.018 BindingDB Entry DOI: 10.7270/Q2KW5H39
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50387782 (CHEMBL2057497) Show SMILES O=C(C1CN(C1)S(=O)(=O)c1cccc2ncccc12)N1CCN(CC1)c1ccncc1 Show InChI InChI=1S/C22H23N5O3S/c28-22(26-13-11-25(12-14-26)18-6-9-23-10-7-18)17-15-27(16-17)31(29,30)21-5-1-4-20-19(21)3-2-8-24-20/h1-10,17H,11-16H2	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by fl...				Bioorg Med Chem Lett 22: 5035-40 (2012) Article DOI: 10.1016/j.bmcl.2012.06.018 BindingDB Entry DOI: 10.7270/Q2KW5H39
					More data for this Ligand-Target Pair