BDBM50387783 CHEMBL2057781

SMILES: O=C(C1CN(C1)S(=O)(=O)c1cccc2OCOc12)N1CC2CN(CC2C1)c1ccncc1

InChI Key: InChIKey=RQHKCOSCAWZZBC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50387783   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50387783 (CHEMBL2057781) Show SMILES O=C(C1CN(C1)S(=O)(=O)c1cccc2OCOc12)N1CC2CN(CC2C1)c1ccncc1 Show InChI InChI=1S/C22H24N4O5S/c27-22(25-10-15-8-24(9-16(15)11-25)18-4-6-23-7-5-18)17-12-26(13-17)32(28,29)20-3-1-2-19-21(20)31-14-30-19/h1-7,15-17H,8-14H2	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by fl...				Bioorg Med Chem Lett 22: 5035-40 (2012) Article DOI: 10.1016/j.bmcl.2012.06.018 BindingDB Entry DOI: 10.7270/Q2KW5H39
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50387783 (CHEMBL2057781) Show SMILES O=C(C1CN(C1)S(=O)(=O)c1cccc2OCOc12)N1CC2CN(CC2C1)c1ccncc1 Show InChI InChI=1S/C22H24N4O5S/c27-22(25-10-15-8-24(9-16(15)11-25)18-4-6-23-7-5-18)17-12-26(13-17)32(28,29)20-3-1-2-19-21(20)31-14-30-19/h1-7,15-17H,8-14H2	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by fl...				Bioorg Med Chem Lett 22: 5035-40 (2012) Article DOI: 10.1016/j.bmcl.2012.06.018 BindingDB Entry DOI: 10.7270/Q2KW5H39
					More data for this Ligand-Target Pair