null

SMILES: COc1ccc(cc1)S(=O)(=O)N(CC#C)[C@H](C(C)C)C(=O)NO

InChI Key: InChIKey=JLXRKMSJFVPFIG-CQSZACIVSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50389094   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50389094 (CHEMBL2064545) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC#C)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C15H20N2O5S/c1-5-10-17(14(11(2)3)15(18)16-19)23(20,21)13-8-6-12(22-4)7-9-13/h1,6-9,11,14,19H,10H2,2-4H3,(H,16,18)/t14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University Hospital M£nster Curated by ChEMBL					Assay Description Inhibition of MMP2 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incuba...				J Med Chem 55: 4714-27 (2012) Article DOI: 10.1021/jm300199g BindingDB Entry DOI: 10.7270/Q2GQ6ZTT
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50389094 (CHEMBL2064545) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC#C)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C15H20N2O5S/c1-5-10-17(14(11(2)3)15(18)16-19)23(20,21)13-8-6-12(22-4)7-9-13/h1,6-9,11,14,19H,10H2,2-4H3,(H,16,18)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University Hospital M£nster Curated by ChEMBL					Assay Description Inhibition of MMP13 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incub...				J Med Chem 55: 4714-27 (2012) Article DOI: 10.1021/jm300199g BindingDB Entry DOI: 10.7270/Q2GQ6ZTT
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50389094 (CHEMBL2064545) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC#C)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C15H20N2O5S/c1-5-10-17(14(11(2)3)15(18)16-19)23(20,21)13-8-6-12(22-4)7-9-13/h1,6-9,11,14,19H,10H2,2-4H3,(H,16,18)/t14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
University Hospital M£nster Curated by ChEMBL					Assay Description Inhibition of MMP9 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incuba...				J Med Chem 55: 4714-27 (2012) Article DOI: 10.1021/jm300199g BindingDB Entry DOI: 10.7270/Q2GQ6ZTT
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50389094 (CHEMBL2064545) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC#C)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C15H20N2O5S/c1-5-10-17(14(11(2)3)15(18)16-19)23(20,21)13-8-6-12(22-4)7-9-13/h1,6-9,11,14,19H,10H2,2-4H3,(H,16,18)/t14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
University Hospital M£nster Curated by ChEMBL					Assay Description Inhibition of MMP8 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incuba...				J Med Chem 55: 4714-27 (2012) Article DOI: 10.1021/jm300199g BindingDB Entry DOI: 10.7270/Q2GQ6ZTT
					More data for this Ligand-Target Pair