null

SMILES: COc1ccc(cc1)S(=O)(=O)N(Cc1cn(CCOCCOCCOCCOc2cccnc2F)nn1)[C@H](C(C)C)C(=O)NO

InChI Key: InChIKey=JXMJSOSLBMBYGM-AREMUKBSSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50389103   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50389103 (CHEMBL2064551) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cn(CCOCCOCCOCCOc2cccnc2F)nn1)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C28H39FN6O9S/c1-21(2)26(28(36)32-37)35(45(38,39)24-8-6-23(40-3)7-9-24)20-22-19-34(33-31-22)11-12-41-13-14-42-15-16-43-17-18-44-25-5-4-10-30-27(25)29/h4-10,19,21,26,37H,11-18,20H2,1-3H3,(H,32,36)/t26-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
University Hospital M£nster Curated by ChEMBL					Assay Description Inhibition of MMP2 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incuba...				J Med Chem 55: 4714-27 (2012) Article DOI: 10.1021/jm300199g BindingDB Entry DOI: 10.7270/Q2GQ6ZTT
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50389103 (CHEMBL2064551) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cn(CCOCCOCCOCCOc2cccnc2F)nn1)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C28H39FN6O9S/c1-21(2)26(28(36)32-37)35(45(38,39)24-8-6-23(40-3)7-9-24)20-22-19-34(33-31-22)11-12-41-13-14-42-15-16-43-17-18-44-25-5-4-10-30-27(25)29/h4-10,19,21,26,37H,11-18,20H2,1-3H3,(H,32,36)/t26-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
University Hospital M£nster Curated by ChEMBL					Assay Description Inhibition of MMP13 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incub...				J Med Chem 55: 4714-27 (2012) Article DOI: 10.1021/jm300199g BindingDB Entry DOI: 10.7270/Q2GQ6ZTT
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50389103 (CHEMBL2064551) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cn(CCOCCOCCOCCOc2cccnc2F)nn1)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C28H39FN6O9S/c1-21(2)26(28(36)32-37)35(45(38,39)24-8-6-23(40-3)7-9-24)20-22-19-34(33-31-22)11-12-41-13-14-42-15-16-43-17-18-44-25-5-4-10-30-27(25)29/h4-10,19,21,26,37H,11-18,20H2,1-3H3,(H,32,36)/t26-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
University Hospital M£nster Curated by ChEMBL					Assay Description Inhibition of MMP9 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incuba...				J Med Chem 55: 4714-27 (2012) Article DOI: 10.1021/jm300199g BindingDB Entry DOI: 10.7270/Q2GQ6ZTT
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50389103 (CHEMBL2064551) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cn(CCOCCOCCOCCOc2cccnc2F)nn1)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C28H39FN6O9S/c1-21(2)26(28(36)32-37)35(45(38,39)24-8-6-23(40-3)7-9-24)20-22-19-34(33-31-22)11-12-41-13-14-42-15-16-43-17-18-44-25-5-4-10-30-27(25)29/h4-10,19,21,26,37H,11-18,20H2,1-3H3,(H,32,36)/t26-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University Hospital M£nster Curated by ChEMBL					Assay Description Inhibition of MMP8 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incuba...				J Med Chem 55: 4714-27 (2012) Article DOI: 10.1021/jm300199g BindingDB Entry DOI: 10.7270/Q2GQ6ZTT
					More data for this Ligand-Target Pair