BDBM50389556 CHEMBL2064157

SMILES: CN(C)C(=O)[C@@H]1Cc2ccccc2N1C(=O)CCN1CCC(CC1)c1ccccc1

InChI Key: InChIKey=PWILLHBMQVNGKL-QHCPKHFHSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50389556   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50389556 (CHEMBL2064157) Show SMILES CN(C)C(=O)[C@@H]1Cc2ccccc2N1C(=O)CCN1CCC(CC1)c1ccccc1 |r| Show InChI InChI=1S/C25H31N3O2/c1-26(2)25(30)23-18-21-10-6-7-11-22(21)28(23)24(29)14-17-27-15-12-20(13-16-27)19-8-4-3-5-9-19/h3-11,20,23H,12-18H2,1-2H3/t23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]N/OFQ from human recombinant ORL1 receptor expressed in HEK293 cells after 45 mins by scintillation proximity assay				Eur J Med Chem 55: 228-42 (2012) Article DOI: 10.1016/j.ejmech.2012.07.021 BindingDB Entry DOI: 10.7270/Q2TT4S1T
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50389556 (CHEMBL2064157) Show SMILES CN(C)C(=O)[C@@H]1Cc2ccccc2N1C(=O)CCN1CCC(CC1)c1ccccc1 |r| Show InChI InChI=1S/C25H31N3O2/c1-26(2)25(30)23-18-21-10-6-7-11-22(21)28(23)24(29)14-17-27-15-12-20(13-16-27)19-8-4-3-5-9-19/h3-11,20,23H,12-18H2,1-2H3/t23-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	80.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from human recombinant MOP receptor expressed in CHO-K1 cells after 45 mins by scintillation proximity assay				Eur J Med Chem 55: 228-42 (2012) Article DOI: 10.1016/j.ejmech.2012.07.021 BindingDB Entry DOI: 10.7270/Q2TT4S1T
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50389556 (CHEMBL2064157) Show SMILES CN(C)C(=O)[C@@H]1Cc2ccccc2N1C(=O)CCN1CCC(CC1)c1ccccc1 |r| Show InChI InChI=1S/C25H31N3O2/c1-26(2)25(30)23-18-21-10-6-7-11-22(21)28(23)24(29)14-17-27-15-12-20(13-16-27)19-8-4-3-5-9-19/h3-11,20,23H,12-18H2,1-2H3/t23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	138	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant ORL1 receptor expressed in HEK293 cells assessed as inhibition of N/OFQ-induced [35S]GTPgammaS binding to al...				Eur J Med Chem 55: 228-42 (2012) Article DOI: 10.1016/j.ejmech.2012.07.021 BindingDB Entry DOI: 10.7270/Q2TT4S1T
					More data for this Ligand-Target Pair