BDBM50390120 CHEMBL2069666

SMILES: COC(C(=O)N\N=C\c1ccc(c(OC)c1)C(F)(F)F)c1ccc2OCCOc2c1

InChI Key: InChIKey=ZAVNBVYHXSHANL-BHGWPJFGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390120   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Mus musculus)	BDBM50390120 (CHEMBL2069666) Show SMILES COC(C(=O)N\N=C\c1ccc(c(OC)c1)C(F)(F)F)c1ccc2OCCOc2c1 Show InChI InChI=1S/C20H19F3N2O5/c1-27-16-9-12(3-5-14(16)20(21,22)23)11-24-25-19(26)18(28-2)13-4-6-15-17(10-13)30-8-7-29-15/h3-6,9-11,18H,7-8H2,1-2H3,(H,25,26)/b24-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Omeros Corp. Curated by ChEMBL					Assay Description Inhibition of mouse PDE10A-mediated hydrolysis of [3H]cGMP to [3H]GMP after 20 mins by scintillation counting				Bioorg Med Chem Lett 22: 5595-9 (2012) Article DOI: 10.1016/j.bmcl.2012.07.007 BindingDB Entry DOI: 10.7270/Q2X63P65
					More data for this Ligand-Target Pair