BDBM50390122 CHEMBL2069663

SMILES: CCOc1cc(\C=N\NC(=O)C(OC)c2ccc3OCCOc3c2)cc(Cl)c1OC

InChI Key: InChIKey=VVJUSDVAPWCZKN-FSJBWODESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390122   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Mus musculus)	BDBM50390122 (CHEMBL2069663) Show SMILES CCOc1cc(\C=N\NC(=O)C(OC)c2ccc3OCCOc3c2)cc(Cl)c1OC Show InChI InChI=1S/C21H23ClN2O6/c1-4-28-18-10-13(9-15(22)20(18)27-3)12-23-24-21(25)19(26-2)14-5-6-16-17(11-14)30-8-7-29-16/h5-6,9-12,19H,4,7-8H2,1-3H3,(H,24,25)/b23-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Omeros Corp. Curated by ChEMBL					Assay Description Inhibition of mouse PDE10A-mediated hydrolysis of [3H]cGMP to [3H]GMP after 20 mins by scintillation counting				Bioorg Med Chem Lett 22: 5595-9 (2012) Article DOI: 10.1016/j.bmcl.2012.07.007 BindingDB Entry DOI: 10.7270/Q2X63P65
					More data for this Ligand-Target Pair