BDBM50390146 CHEMBL2069683

SMILES: COC(C(=O)N\N=C\c1cc(OC)c(Br)c(OC)c1)c1cccnc1

InChI Key: InChIKey=MCXSWRFYWBLGPI-AWQFTUOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390146   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Mus musculus)	BDBM50390146 (CHEMBL2069683) Show SMILES COC(C(=O)N\N=C\c1cc(OC)c(Br)c(OC)c1)c1cccnc1 Show InChI InChI=1S/C17H18BrN3O4/c1-23-13-7-11(8-14(24-2)15(13)18)9-20-21-17(22)16(25-3)12-5-4-6-19-10-12/h4-10,16H,1-3H3,(H,21,22)/b20-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Omeros Corp. Curated by ChEMBL					Assay Description Inhibition of mouse PDE10A-mediated hydrolysis of [3H]cGMP to [3H]GMP after 20 mins by scintillation counting				Bioorg Med Chem Lett 22: 5595-9 (2012) Article DOI: 10.1016/j.bmcl.2012.07.007 BindingDB Entry DOI: 10.7270/Q2X63P65
					More data for this Ligand-Target Pair