BDBM50390379 CHEMBL2070920

SMILES: CC(c1ccc2[nH]ccc2c1)n1nnc2c(N)nc(nc12)C1CC1

InChI Key: InChIKey=QABRXFRQVAFEGX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390379   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 8 (Homo sapiens (Human))	BDBM50390379 (CHEMBL2070920) Show SMILES CC(c1ccc2[nH]ccc2c1)n1nnc2c(N)nc(nc12)C1CC1 Show InChI InChI=1S/C17H17N7/c1-9(11-4-5-13-12(8-11)6-7-19-13)24-17-14(22-23-24)15(18)20-16(21-17)10-2-3-10/h4-10,19H,2-3H2,1H3,(H2,18,20,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	31.7	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PDE8B expressed in Sf9 insect cells				Bioorg Med Chem Lett 22: 5721-6 (2012) Article DOI: 10.1016/j.bmcl.2012.06.079 BindingDB Entry DOI: 10.7270/Q2J67J0X
					More data for this Ligand-Target Pair