BDBM50390591 CHEMBL2069496

SMILES: O=C(Nc1cc(c[nH]c1=O)-c1ccncc1)[C@H](Cc1ccccc1)NCC1CC1

InChI Key: InChIKey=MBYMWYUCLHWEIM-FQEVSTJZSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390591   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Probable G-protein coupled receptor 142 (Homo sapiens (Human))	BDBM50390591 (CHEMBL2069496) Show SMILES O=C(Nc1cc(c[nH]c1=O)-c1ccncc1)[C@H](Cc1ccccc1)NCC1CC1 |r| Show InChI InChI=1S/C23H24N4O2/c28-22-21(13-19(15-26-22)18-8-10-24-11-9-18)27-23(29)20(25-14-17-6-7-17)12-16-4-2-1-3-5-16/h1-5,8-11,13,15,17,20,25H,6-7,12,14H2,(H,26,28)(H,27,29)/t20-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	760	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...				Bioorg Med Chem Lett 22: 5942-7 (2012) Article DOI: 10.1016/j.bmcl.2012.07.063 BindingDB Entry DOI: 10.7270/Q2VH5PXT
					More data for this Ligand-Target Pair