BDBM50390647 CHEMBL2069721

SMILES: CCOC(=O)Cc1csc(NS(=O)(=O)c2cc(cs2)-c2nc3ccccc3s2)n1

InChI Key: InChIKey=QJBNNBJQOAMNPT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390647   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-Dependent Kinase 5 (CDK5) (Homo sapiens (Human))	BDBM50390647 (CHEMBL2069721) Show SMILES CCOC(=O)Cc1csc(NS(=O)(=O)c2cc(cs2)-c2nc3ccccc3s2)n1 Show InChI InChI=1S/C18H15N3O4S4/c1-2-25-15(22)8-12-10-27-18(19-12)21-29(23,24)16-7-11(9-26-16)17-20-13-5-3-4-6-14(13)28-17/h3-7,9-10H,2,8H2,1H3,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant Cdk5/p25 incubated for 15 mins by scintillation proximity assay				Bioorg Med Chem Lett 22: 5919-23 (2012) Article DOI: 10.1016/j.bmcl.2012.07.068 BindingDB Entry DOI: 10.7270/Q2G73FTN
					More data for this Ligand-Target Pair