BDBM50390669 CHEMBL2070197

SMILES: Brc1cccc(Nc2ncnc3ccc(NCc4ccc5OCOc5c4)cc23)c1

InChI Key: InChIKey=DRIQKFZQTNZHHK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390669   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50390669 (CHEMBL2070197) Show SMILES Brc1cccc(Nc2ncnc3ccc(NCc4ccc5OCOc5c4)cc23)c1 Show InChI InChI=1S/C22H17BrN4O2/c23-15-2-1-3-17(9-15)27-22-18-10-16(5-6-19(18)25-12-26-22)24-11-14-4-7-20-21(8-14)29-13-28-20/h1-10,12,24H,11,13H2,(H,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of EGFR in human A431 cell lysate using tyrosine/glutamic acid polymer as substrate by ELISA				Bioorg Med Chem Lett 22: 5870-5 (2012) Article DOI: 10.1016/j.bmcl.2012.07.079 BindingDB Entry DOI: 10.7270/Q26T0NRG
					More data for this Ligand-Target Pair