BDBM50390671 CHEMBL2070192

SMILES: Brc1cccc(Nc2ncnc3ccc(NCc4ccc5OCCOc5c4)cc23)c1

InChI Key: InChIKey=HCKKSKAPOHHGNB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390671   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50390671 (CHEMBL2070192) Show SMILES Brc1cccc(Nc2ncnc3ccc(NCc4ccc5OCCOc5c4)cc23)c1 Show InChI InChI=1S/C23H19BrN4O2/c24-16-2-1-3-18(11-16)28-23-19-12-17(5-6-20(19)26-14-27-23)25-13-15-4-7-21-22(10-15)30-9-8-29-21/h1-7,10-12,14,25H,8-9,13H2,(H,26,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of EGFR in human A431 cell lysate using tyrosine/glutamic acid polymer as substrate by ELISA				Bioorg Med Chem Lett 22: 5870-5 (2012) Article DOI: 10.1016/j.bmcl.2012.07.079 BindingDB Entry DOI: 10.7270/Q26T0NRG
					More data for this Ligand-Target Pair