BDBM50390798 CHEMBL2070634

SMILES: COc1ccc2nnc3c(C)nc(-c4ccccc4C)n3c2n1

InChI Key: InChIKey=XLZOIIVTFPXQAK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390798   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50390798 (CHEMBL2070634) Show SMILES COc1ccc2nnc3c(C)nc(-c4ccccc4C)n3c2n1 Show InChI InChI=1S/C17H15N5O/c1-10-6-4-5-7-12(10)16-18-11(2)15-21-20-13-8-9-14(23-3)19-17(13)22(15)16/h4-9H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47.6	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis				Bioorg Med Chem Lett 22: 5876-84 (2012) Article DOI: 10.1016/j.bmcl.2012.07.076 BindingDB Entry DOI: 10.7270/Q2FB5413
					More data for this Ligand-Target Pair