BDBM50391316 CHEMBL422017

SMILES: OC(=O)CCC\C=C(\c1cccnc1)c1cccc(CCCNS(=O)(=O)c2ccccc2)c1

InChI Key: InChIKey=WHSSOYNNHOWWJE-MFKUBSTISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50391316   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human))	BDBM50391316 (CHEMBL422017) Show SMILES OC(=O)CCC\C=C(\c1cccnc1)c1cccc(CCCNS(=O)(=O)c2ccccc2)c1 Show InChI InChI=1S/C26H28N2O4S/c29-26(30)16-5-4-15-25(23-12-8-17-27-20-23)22-11-6-9-21(19-22)10-7-18-28-33(31,32)24-13-2-1-3-14-24/h1-3,6,8-9,11-15,17,19-20,28H,4-5,7,10,16,18H2,(H,29,30)/b25-15+	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of collagen-induced thromboxane A2 production in human whole blood				Bioorg Med Chem Lett 1: 699-704 (1991) Article DOI: 10.1016/S0960-894X(01)81051-9 BindingDB Entry DOI: 10.7270/Q2WD41RM
					More data for this Ligand-Target Pair