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SMILES: CC(=O)Nc1cc(N)cc(c1)-c1cnc2[nH]cc(-c3ccncc3)c2c1

InChI Key: InChIKey=BMVDRHIIZZFEIJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50391950   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
High affinity nerve growth factor receptor


(Homo sapiens (Human))		BDBM50391950
PNG
(CHEMBL2152289)
Show SMILES CC(=O)Nc1cc(N)cc(c1)-c1cnc2[nH]cc(-c3ccncc3)c2c1
Show InChI InChI=1S/C20H17N5O/c1-12(26)25-17-7-14(6-16(21)9-17)15-8-18-19(11-24-20(18)23-10-15)13-2-4-22-5-3-13/h2-11H,21H2,1H3,(H,23,24)(H,25,26)
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Article
PubMed
n/an/a 5.41n/an/an/an/an/an/a



Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL


Assay Description
Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrate

J Med Chem 55: 5337-49 (2012)


Article DOI: 10.1021/jm3002982
BindingDB Entry DOI: 10.7270/Q2JM2BQ3
More data for this
Ligand-Target Pair