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SMILES: Nc1ccc(NS(=O)(=O)c2ccccc2)c(c1)-c1cnc2[nH]cc(-c3ccncc3)c2c1

InChI Key: InChIKey=POKMFTRMOKZDQD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50391952   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
High affinity nerve growth factor receptor


(Homo sapiens (Human))		BDBM50391952
PNG
(CHEMBL2152291)
Show SMILES Nc1ccc(NS(=O)(=O)c2ccccc2)c(c1)-c1cnc2[nH]cc(-c3ccncc3)c2c1
Show InChI InChI=1S/C24H19N5O2S/c25-18-6-7-23(29-32(30,31)19-4-2-1-3-5-19)20(13-18)17-12-21-22(15-28-24(21)27-14-17)16-8-10-26-11-9-16/h1-15,29H,25H2,(H,27,28)
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Article
PubMed
n/an/a 3.17E+3n/an/an/an/an/an/a



Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL


Assay Description
Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrate

J Med Chem 55: 5337-49 (2012)


Article DOI: 10.1021/jm3002982
BindingDB Entry DOI: 10.7270/Q2JM2BQ3
More data for this
Ligand-Target Pair