BDBM50391960 CHEMBL2152269

SMILES: Nc1cncc(c1)-c1cnc2[nH]cc(-c3ccncc3)c2c1

InChI Key: InChIKey=FVHOGNFYVWIKLP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50391960   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50391960 (CHEMBL2152269) Show SMILES Nc1cncc(c1)-c1cnc2[nH]cc(-c3ccncc3)c2c1 Show InChI InChI=1S/C17H13N5/c18-14-5-12(7-20-9-14)13-6-15-16(10-22-17(15)21-8-13)11-1-3-19-4-2-11/h1-10H,18H2,(H,21,22)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	69.6	n/a	n/a	n/a	n/a	n/a	n/a
Korea Advanced Institute of Science and Technology (KAIST) Curated by ChEMBL					Assay Description Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrate				J Med Chem 55: 5337-49 (2012) Article DOI: 10.1021/jm3002982 BindingDB Entry DOI: 10.7270/Q2JM2BQ3
					More data for this Ligand-Target Pair