BDBM50391962 CHEMBL2152271
SMILES: CN(C)c1cccc(c1)-c1cnc2[nH]cc(-c3ccncc3)c2c1
InChI Key: InChIKey=QLGACVZCLAAVSH-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM50391962![]() (CHEMBL2152271) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 26.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Advanced Institute of Science and Technology (KAIST) Curated by ChEMBL | Assay Description Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrate | J Med Chem 55: 5337-49 (2012) Article DOI: 10.1021/jm3002982 BindingDB Entry DOI: 10.7270/Q2JM2BQ3 | |||||||||||
More data for this Ligand-Target Pair |