BDBM50391976 CHEMBL2152285

SMILES: Nc1cc(NS(=O)(=O)c2ccccc2)cc(c1)-c1cnc2[nH]cc(-c3ccncc3)c2c1

InChI Key: InChIKey=SYKRQJDYTBBJQM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50391976   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50391976 (CHEMBL2152285) Show SMILES Nc1cc(NS(=O)(=O)c2ccccc2)cc(c1)-c1cnc2[nH]cc(-c3ccncc3)c2c1 Show InChI InChI=1S/C24H19N5O2S/c25-19-10-17(11-20(13-19)29-32(30,31)21-4-2-1-3-5-21)18-12-22-23(15-28-24(22)27-14-18)16-6-8-26-9-7-16/h1-15,29H,25H2,(H,27,28)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
Korea Advanced Institute of Science and Technology (KAIST) Curated by ChEMBL					Assay Description Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrate				J Med Chem 55: 5337-49 (2012) Article DOI: 10.1021/jm3002982 BindingDB Entry DOI: 10.7270/Q2JM2BQ3
					More data for this Ligand-Target Pair