BDBM50393882 CHEMBL2158243
SMILES: Brc1ccc(CSc2ccc3C(=O)NC(=O)c3c2)cc1
InChI Key: InChIKey=VWQLWWBXGIQDME-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM50393882![]() (CHEMBL2158243) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 676 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North-West University | Assay Description For the A2a receptor binding study, the incubation contained 10 mg of the original tissue weight of the striatal membranes, 4 nM [3H]NECA, 50 nM CPA,... | Bioorg Chem 59: 117-23 (2015) Article DOI: 10.1016/j.bioorg.2015.02.005 BindingDB Entry DOI: 10.7270/Q22J69KC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase (flavin-containing) A (Homo sapiens (Human)) | BDBM50393882![]() (CHEMBL2158243) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 273 | n/a | n/a | n/a | n/a | n/a | n/a |
North-West University Curated by ChEMBL | Assay Description Inhibition of human recombinant MAOA using kynuramine as substrate assessed as formation of 4-hydroxyquinoline after 20 mins by fluorescence spectrop... | Bioorg Med Chem Lett 22: 6632-5 (2012) Article DOI: 10.1016/j.bmcl.2012.08.113 BindingDB Entry DOI: 10.7270/Q2RJ4KK4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM50393882![]() (CHEMBL2158243) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.40 | n/a | n/a | n/a | n/a | n/a | n/a |
North-West University Curated by ChEMBL | Assay Description Inhibition of human recombinant MAOB using kynuramine as substrate assessed as formation of 4-hydroxyquinoline after 20 mins by fluorescence spectrop... | Bioorg Med Chem Lett 22: 6632-5 (2012) Article DOI: 10.1016/j.bmcl.2012.08.113 BindingDB Entry DOI: 10.7270/Q2RJ4KK4 | |||||||||||
More data for this Ligand-Target Pair |