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SMILES: COCc1ccccc1NC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1

InChI Key: InChIKey=MQNDNJDYZVJFQY-JOCHJYFZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50394479   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50394479
PNG
(CHEMBL2160097)
Show SMILES COCc1ccccc1NC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1 |r|
Show InChI InChI=1S/C24H26FN3O2/c1-30-16-20-4-2-3-5-23(20)27-24(29)26-22-10-11-28(15-22)14-17-6-7-19-13-21(25)9-8-18(19)12-17/h2-9,12-13,22H,10-11,14-16H2,1H3,(H2,26,27,29)/t22-/m1/s1
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n/an/a 23n/an/an/an/an/an/a



Toray Industries, Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at CCR3 receptor

Bioorg Med Chem Lett 22: 6876-81 (2012)


Article DOI: 10.1016/j.bmcl.2012.09.035
BindingDB Entry DOI: 10.7270/Q2QC04MN
More data for this
Ligand-Target Pair