BDBM50394547 CHEMBL2160190

SMILES: CC(C)c1n[nH]c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccccc1C(F)(F)F

InChI Key: InChIKey=VESIRPJRGWDPGB-YRHQEJDOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50394547   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 1 (SGLT1) (Homo sapiens (Human))	BDBM50394547 (CHEMBL2160190) Show SMILES CC(C)c1n[nH]c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccccc1C(F)(F)F |r| Show InChI InChI=1S/C20H25F3N2O6/c1-9(2)14-11(7-10-5-3-4-6-12(10)20(21,22)23)18(25-24-14)31-19-17(29)16(28)15(27)13(8-26)30-19/h3-6,9,13,15-17,19,26-29H,7-8H2,1-2H3,(H,24,25)/t13-,15-,16+,17-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction of [14C]-AMG uptake				Bioorg Med Chem 20: 6598-612 (2012) Article DOI: 10.1016/j.bmc.2012.09.037 BindingDB Entry DOI: 10.7270/Q26D5V36
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50394547 (CHEMBL2160190) Show SMILES CC(C)c1n[nH]c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccccc1C(F)(F)F |r| Show InChI InChI=1S/C20H25F3N2O6/c1-9(2)14-11(7-10-5-3-4-6-12(10)20(21,22)23)18(25-24-14)31-19-17(29)16(28)15(27)13(8-26)30-19/h3-6,9,13,15-17,19,26-29H,7-8H2,1-2H3,(H,24,25)/t13-,15-,16+,17-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction of [14C]-AMG uptake				Bioorg Med Chem 20: 6598-612 (2012) Article DOI: 10.1016/j.bmc.2012.09.037 BindingDB Entry DOI: 10.7270/Q26D5V36
					More data for this Ligand-Target Pair