BDBM50394550 CHEMBL2160193
SMILES: CC(C)c1n[nH]c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccccc1
InChI Key: InChIKey=KOUKLJGYBYZYJQ-YRHQEJDOSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50394550![]() (CHEMBL2160193) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction of [14C]-AMG uptake | Bioorg Med Chem 20: 6598-612 (2012) Article DOI: 10.1016/j.bmc.2012.09.037 BindingDB Entry DOI: 10.7270/Q26D5V36 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (SGLT1) (Homo sapiens (Human)) | BDBM50394550![]() (CHEMBL2160193) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 738 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Curated by ChEMBL | Assay Description Inhibition of human SGLT1 expressed in COS7 cells assessed as inhibition [14C]-AMG cellular uptake | Bioorg Med Chem 21: 748-65 (2013) Article DOI: 10.1016/j.bmc.2012.11.041 BindingDB Entry DOI: 10.7270/Q2445NS9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50394550![]() (CHEMBL2160193) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Curated by ChEMBL | Assay Description Inhibition of human SGLT2 expressed in COS7 cells assessed as inhibition [14C]-AMG cellular uptake | Bioorg Med Chem 21: 748-65 (2013) Article DOI: 10.1016/j.bmc.2012.11.041 BindingDB Entry DOI: 10.7270/Q2445NS9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (SGLT1) (Homo sapiens (Human)) | BDBM50394550![]() (CHEMBL2160193) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 738 | n/a | n/a | n/a | n/a | n/a | n/a |
Kissei Pharmaceutical Company Curated by ChEMBL | Assay Description Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction of [14C]-AMG uptake | Bioorg Med Chem 20: 6598-612 (2012) Article DOI: 10.1016/j.bmc.2012.09.037 BindingDB Entry DOI: 10.7270/Q26D5V36 | |||||||||||
More data for this Ligand-Target Pair |