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BDBM50394646 CHEMBL2164608

SMILES: COc1cc(C\C=C\c2ccccc2\C=C\C(O)=O)ccc1OCCn1cc2ccccc2c1C#N

InChI Key: InChIKey=MDRAJBLIYXCTEC-BTSHEXGNSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50394646   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin E2 receptor


(Homo sapiens (Human))
BDBM50394646
PNG
(CHEMBL2164608)
Show SMILES COc1cc(C\C=C\c2ccccc2\C=C\C(O)=O)ccc1OCCn1cc2ccccc2c1C#N
Show InChI InChI=1S/C30H26N2O4/c1-35-29-19-22(7-6-11-23-8-2-3-9-24(23)14-16-30(33)34)13-15-28(29)36-18-17-32-21-25-10-4-5-12-26(25)27(32)20-31/h2-6,8-16,19,21H,7,17-18H2,1H3,(H,33,34)/b11-6+,16-14+
PDB

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PC sid
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18n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from human EP3R expressed in chem1 cells after 2hrs by beta counting


ACS Med Chem Lett 3: 774-779 (2012)


Article DOI: 10.1021/ml300191g
BindingDB Entry DOI: 10.7270/Q2DZ09D3
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50394646
PNG
(CHEMBL2164608)
Show SMILES COc1cc(C\C=C\c2ccccc2\C=C\C(O)=O)ccc1OCCn1cc2ccccc2c1C#N
Show InChI InChI=1S/C30H26N2O4/c1-35-29-19-22(7-6-11-23-8-2-3-9-24(23)14-16-30(33)34)13-15-28(29)36-18-17-32-21-25-10-4-5-12-26(25)27(32)20-31/h2-6,8-16,19,21H,7,17-18H2,1H3,(H,33,34)/b11-6+,16-14+
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3.18E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from human EP4R expressed in chem1 cells after 2hrs by beta counting


ACS Med Chem Lett 3: 774-779 (2012)


Article DOI: 10.1021/ml300191g
BindingDB Entry DOI: 10.7270/Q2DZ09D3
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM50394646
PNG
(CHEMBL2164608)
Show SMILES COc1cc(C\C=C\c2ccccc2\C=C\C(O)=O)ccc1OCCn1cc2ccccc2c1C#N
Show InChI InChI=1S/C30H26N2O4/c1-35-29-19-22(7-6-11-23-8-2-3-9-24(23)14-16-30(33)34)13-15-28(29)36-18-17-32-21-25-10-4-5-12-26(25)27(32)20-31/h2-6,8-16,19,21H,7,17-18H2,1H3,(H,33,34)/b11-6+,16-14+
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4.26E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from human EP2R expressed in chem1 cells after 2hrs by beta counting


ACS Med Chem Lett 3: 774-779 (2012)


Article DOI: 10.1021/ml300191g
BindingDB Entry DOI: 10.7270/Q2DZ09D3
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50394646
PNG
(CHEMBL2164608)
Show SMILES COc1cc(C\C=C\c2ccccc2\C=C\C(O)=O)ccc1OCCn1cc2ccccc2c1C#N
Show InChI InChI=1S/C30H26N2O4/c1-35-29-19-22(7-6-11-23-8-2-3-9-24(23)14-16-30(33)34)13-15-28(29)36-18-17-32-21-25-10-4-5-12-26(25)27(32)20-31/h2-6,8-16,19,21H,7,17-18H2,1H3,(H,33,34)/b11-6+,16-14+
KEGG

UniProtKB/SwissProt

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antibodypedia
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1.60E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from human EP1R expressed in chem1 cells after 2hrs by beta counting


ACS Med Chem Lett 3: 774-779 (2012)


Article DOI: 10.1021/ml300191g
BindingDB Entry DOI: 10.7270/Q2DZ09D3
More data for this
Ligand-Target Pair