BDBM50395337 CHEMBL2164385

SMILES: Brc1cccc(CNC(=O)C2N(CCc3ccccn3)C(=O)c3ccccc23)c1

InChI Key: InChIKey=RERHIKRBDUEBLN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50395337   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50395337 (CHEMBL2164385) Show SMILES Brc1cccc(CNC(=O)C2N(CCc3ccccn3)C(=O)c3ccccc23)c1 Show InChI InChI=1S/C23H20BrN3O2/c24-17-7-5-6-16(14-17)15-26-22(28)21-19-9-1-2-10-20(19)23(29)27(21)13-11-18-8-3-4-12-25-18/h1-10,12,14,21H,11,13,15H2,(H,26,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human NaV1.7 alpha subunit expressed in HEK293 cells at -65 mV holding potential by patch clamp electrophysiological assay				J Med Chem 55: 6866-80 (2012) Article DOI: 10.1021/jm300623u BindingDB Entry DOI: 10.7270/Q2M909SB
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50395337 (CHEMBL2164385) Show SMILES Brc1cccc(CNC(=O)C2N(CCc3ccccn3)C(=O)c3ccccc23)c1 Show InChI InChI=1S/C23H20BrN3O2/c24-17-7-5-6-16(14-17)15-26-22(28)21-19-9-1-2-10-20(19)23(29)27(21)13-11-18-8-3-4-12-25-18/h1-10,12,14,21H,11,13,15H2,(H,26,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human NaV1.5 alpha subunit expressed in CHOK1 cells at -90 mV holding potential by patch clamp electrophysiological assay				J Med Chem 55: 6866-80 (2012) Article DOI: 10.1021/jm300623u BindingDB Entry DOI: 10.7270/Q2M909SB
					More data for this Ligand-Target Pair