BDBM50395745 CHEMBL2164830

SMILES: CN1CCN(CC(=O)NC2(C(=O)Nc3cc(Cl)ccc23)c2ccc(Cl)c(Cl)c2)CC1

InChI Key: InChIKey=GYCGPXMDDMVYNV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50395745   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin receptor (Homo sapiens (Human))	BDBM50395745 (CHEMBL2164830) Show SMILES CN1CCN(CC(=O)NC2(C(=O)Nc3cc(Cl)ccc23)c2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C21H21Cl3N4O2/c1-27-6-8-28(9-7-27)12-19(29)26-21(13-2-5-16(23)17(24)10-13)15-4-3-14(22)11-18(15)25-20(21)30/h2-5,10-11H,6-9,12H2,1H3,(H,25,30)(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	111	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Research Curated by ChEMBL					Assay Description Antagonist activity at human GHSR1 expressed in CHO-CREluc cells after 4 hrs by Luciferase reporter assay				Bioorg Med Chem 20: 5623-36 (2012) Article DOI: 10.1016/j.bmc.2012.07.018 BindingDB Entry DOI: 10.7270/Q2HD7WS4
					More data for this Ligand-Target Pair