BDBM50395772 CHEMBL2164492

SMILES: CN1CCN(CC(=O)NC2(C(=O)Nc3cc(Cl)c(Cl)cc23)c2ccc(cc2)C(C)(C)C)CC1

InChI Key: InChIKey=GMPYEOWYKXIMNB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50395772   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin receptor (Homo sapiens (Human))	BDBM50395772 (CHEMBL2164492) Show SMILES CN1CCN(CC(=O)NC2(C(=O)Nc3cc(Cl)c(Cl)cc23)c2ccc(cc2)C(C)(C)C)CC1 Show InChI InChI=1S/C25H30Cl2N4O2/c1-24(2,3)16-5-7-17(8-6-16)25(29-22(32)15-31-11-9-30(4)10-12-31)18-13-19(26)20(27)14-21(18)28-23(25)33/h5-8,13-14H,9-12,15H2,1-4H3,(H,28,33)(H,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Research Curated by ChEMBL					Assay Description Antagonist activity at human GHSR1 expressed in CHO-CREluc cells after 4 hrs by Luciferase reporter assay				Bioorg Med Chem 20: 5623-36 (2012) Article DOI: 10.1016/j.bmc.2012.07.018 BindingDB Entry DOI: 10.7270/Q2HD7WS4
					More data for this Ligand-Target Pair