BDBM50397587 CHEMBL2171489

SMILES: CCOc1ccc2c(cc(cc2n1)-c1cc2ccccc2nc1N1CCOCC1)C(C)C

InChI Key: InChIKey=RSTOHUDMHLBFLR-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50397587   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-related protein A1 (Homo sapiens (Human))	BDBM50397587 (CHEMBL2171489) Show SMILES CCOc1ccc2c(cc(cc2n1)-c1cc2ccccc2nc1N1CCOCC1)C(C)C Show InChI InChI=1S/C27H29N3O2/c1-4-32-26-10-9-21-22(18(2)3)16-20(17-25(21)28-26)23-15-19-7-5-6-8-24(19)29-27(23)30-11-13-31-14-12-30/h5-10,15-18H,4,11-14H2,1-3H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of GST-tagged recombinant Bfl1 interaction with biotinylated Bim peptide by ELISA based competitive binding assay				Eur J Med Chem 57: 112-25 (2012) Article DOI: 10.1016/j.ejmech.2012.09.012 BindingDB Entry DOI: 10.7270/Q2B8598P
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50397587 (CHEMBL2171489) Show SMILES CCOc1ccc2c(cc(cc2n1)-c1cc2ccccc2nc1N1CCOCC1)C(C)C Show InChI InChI=1S/C27H29N3O2/c1-4-32-26-10-9-21-22(18(2)3)16-20(17-25(21)28-26)23-15-19-7-5-6-8-24(19)29-27(23)30-11-13-31-14-12-30/h5-10,15-18H,4,11-14H2,1-3H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of GST-tagged recombinant Bcl2 interaction with biotinylated Bim peptide by ELISA based competitive binding assay				Eur J Med Chem 57: 112-25 (2012) Article DOI: 10.1016/j.ejmech.2012.09.012 BindingDB Entry DOI: 10.7270/Q2B8598P
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM50397587 (CHEMBL2171489) Show SMILES CCOc1ccc2c(cc(cc2n1)-c1cc2ccccc2nc1N1CCOCC1)C(C)C Show InChI InChI=1S/C27H29N3O2/c1-4-32-26-10-9-21-22(18(2)3)16-20(17-25(21)28-26)23-15-19-7-5-6-8-24(19)29-27(23)30-11-13-31-14-12-30/h5-10,15-18H,4,11-14H2,1-3H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of GST-tagged recombinant Mcl1 interaction with biotinylated Bim peptide by ELISA based competitive binding assay				Eur J Med Chem 57: 112-25 (2012) Article DOI: 10.1016/j.ejmech.2012.09.012 BindingDB Entry DOI: 10.7270/Q2B8598P
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50397587 (CHEMBL2171489) Show SMILES CCOc1ccc2c(cc(cc2n1)-c1cc2ccccc2nc1N1CCOCC1)C(C)C Show InChI InChI=1S/C27H29N3O2/c1-4-32-26-10-9-21-22(18(2)3)16-20(17-25(21)28-26)23-15-19-7-5-6-8-24(19)29-27(23)30-11-13-31-14-12-30/h5-10,15-18H,4,11-14H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.46E+4	n/a	n/a	n/a	n/a
Clermont Universit£ Curated by ChEMBL					Assay Description Inhibition of GST-tagged recombinant Bcl-XL interaction with biotinylated Bim peptide by ELISA based competitive binding assay				Eur J Med Chem 57: 112-25 (2012) Article DOI: 10.1016/j.ejmech.2012.09.012 BindingDB Entry DOI: 10.7270/Q2B8598P
					More data for this Ligand-Target Pair