BDBM50397972 CHEMBL2180442

SMILES: Cc1nc2ccccc2nc1OCc1cc(OC2CCOCC2)nc(n1)N1CCCC1

InChI Key: InChIKey=OEOOJXARIPUPTL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50397972   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50397972 (CHEMBL2180442) Show SMILES Cc1nc2ccccc2nc1OCc1cc(OC2CCOCC2)nc(n1)N1CCCC1 Show InChI InChI=1S/C23H27N5O3/c1-16-22(26-20-7-3-2-6-19(20)24-16)30-15-17-14-21(31-18-8-12-29-13-9-18)27-23(25-17)28-10-4-5-11-28/h2-3,6-7,14,18H,4-5,8-13,15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PDE10A				J Med Chem 55: 7299-331 (2012) Article DOI: 10.1021/jm3004976 BindingDB Entry DOI: 10.7270/Q2C24XJK
					More data for this Ligand-Target Pair