BDBM50397975 CHEMBL2180439

SMILES: Cc1nc2ccccc2nc1CCc1nc(cc(n1)C(=O)NC[C@@H]1CCCO1)N1CCCC1

InChI Key: InChIKey=PMHFGEMRSKIZLB-SFHVURJKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50397975   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50397975 (CHEMBL2180439) Show SMILES Cc1nc2ccccc2nc1CCc1nc(cc(n1)C(=O)NC[C@@H]1CCCO1)N1CCCC1 |r| Show InChI InChI=1S/C25H30N6O2/c1-17-19(28-21-9-3-2-8-20(21)27-17)10-11-23-29-22(15-24(30-23)31-12-4-5-13-31)25(32)26-16-18-7-6-14-33-18/h2-3,8-9,15,18H,4-7,10-14,16H2,1H3,(H,26,32)/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PDE10A				J Med Chem 55: 7299-331 (2012) Article DOI: 10.1021/jm3004976 BindingDB Entry DOI: 10.7270/Q2C24XJK
					More data for this Ligand-Target Pair