BDBM50398025 CHEMBL2181094

SMILES: FC(F)(F)c1cccc(c1)N1CCN(CC1)S(=O)(=O)c1ccc2NC(=O)Cc2c1

InChI Key: InChIKey=BVJMWXIGDMKQEZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50398025   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal alpha-glucosidase (Homo sapiens (Human))	BDBM50398025 (CHEMBL2181094) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CC1)S(=O)(=O)c1ccc2NC(=O)Cc2c1 Show InChI InChI=1S/C19H18F3N3O3S/c20-19(21,22)14-2-1-3-15(12-14)24-6-8-25(9-7-24)29(27,28)16-4-5-17-13(10-16)11-18(26)23-17/h1-5,10,12H,6-9,11H2,(H,23,26)	PDB NCI pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.49E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assay				J Med Chem 55: 7546-59 (2012) Article DOI: 10.1021/jm3005543 BindingDB Entry DOI: 10.7270/Q27945SS
					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Homo sapiens (Human))	BDBM50398025 (CHEMBL2181094) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CC1)S(=O)(=O)c1ccc2NC(=O)Cc2c1 Show InChI InChI=1S/C19H18F3N3O3S/c20-19(21,22)14-2-1-3-15(12-14)24-6-8-25(9-7-24)29(27,28)16-4-5-17-13(10-16)11-18(26)23-17/h1-5,10,12H,6-9,11H2,(H,23,26)	PDB NCI pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.49E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assay				J Med Chem 55: 7546-59 (2012) Article DOI: 10.1021/jm3005543 BindingDB Entry DOI: 10.7270/Q27945SS
					More data for this Ligand-Target Pair