BDBM50398060 CHEMBL2181931

SMILES: COc1cc(ccc1S(N)(=O)=O)C(=O)Nc1ccc(c(CCN(C)C2CC2)c1)-c1ccccc1OC(F)(F)F

InChI Key: InChIKey=OZNCREFZUAWJQT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50398060   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
mineralocorticoid (RAT)	BDBM50398060 (CHEMBL2181931) Show SMILES COc1cc(ccc1S(N)(=O)=O)C(=O)Nc1ccc(c(CCN(C)C2CC2)c1)-c1ccccc1OC(F)(F)F Show InChI InChI=1S/C27H28F3N3O5S/c1-33(20-9-10-20)14-13-17-15-19(8-11-21(17)22-5-3-4-6-23(22)38-27(28,29)30)32-26(34)18-7-12-25(39(31,35)36)24(16-18)37-2/h3-8,11-12,15-16,20H,9-10,13-14H2,1-2H3,(H,32,34)(H2,31,35,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]Aldosterone C from rat mineralocorticoid receptor by liquid scintillation counter analysis				J Med Chem 55: 7957-66 (2012) Article DOI: 10.1021/jm300806c BindingDB Entry DOI: 10.7270/Q2QC04N3
					More data for this Ligand-Target Pair