BDBM50399723 CHEMBL2178974

SMILES: CC(C)(C)OC(=O)N1CCN(Cc2cn(nn2)[C@H]2C[C@H](N(C2)C(=O)CCCc2ccccc2)C(=O)N2CCCC2)CC1

InChI Key: InChIKey=LPMUXXBRNGPFML-SVBPBHIXSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50399723   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50399723 (CHEMBL2178974) Show SMILES CC(C)(C)OC(=O)N1CCN(Cc2cn(nn2)[C@H]2C[C@H](N(C2)C(=O)CCCc2ccccc2)C(=O)N2CCCC2)CC1 |r| Show InChI InChI=1S/C31H45N7O4/c1-31(2,3)42-30(41)36-18-16-34(17-19-36)21-25-22-38(33-32-25)26-20-27(29(40)35-14-7-8-15-35)37(23-26)28(39)13-9-12-24-10-5-4-6-11-24/h4-6,10-11,22,26-27H,7-9,12-21,23H2,1-3H3/t26-,27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of human seminal plasma DPP4 assessed as pNA release from Gly-Pro-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...				J Med Chem 55: 9856-67 (2012) Article DOI: 10.1021/jm301060g BindingDB Entry DOI: 10.7270/Q2SN0B3S
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Sus scrofa)	BDBM50399723 (CHEMBL2178974) Show SMILES CC(C)(C)OC(=O)N1CCN(Cc2cn(nn2)[C@H]2C[C@H](N(C2)C(=O)CCCc2ccccc2)C(=O)N2CCCC2)CC1 |r| Show InChI InChI=1S/C31H45N7O4/c1-31(2,3)42-30(41)36-18-16-34(17-19-36)21-25-22-38(33-32-25)26-20-27(29(40)35-14-7-8-15-35)37(23-26)28(39)13-9-12-24-10-5-4-6-11-24/h4-6,10-11,22,26-27H,7-9,12-21,23H2,1-3H3/t26-,27-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of pig PREP expressed in Escherichia coli using Z-Gly-Pro-p-nitroanilide substrate				J Med Chem 55: 9856-67 (2012) Article DOI: 10.1021/jm301060g BindingDB Entry DOI: 10.7270/Q2SN0B3S
					More data for this Ligand-Target Pair
Fibroblast activation protein (FAP) (Mus musculus (Mouse))	BDBM50399723 (CHEMBL2178974) Show SMILES CC(C)(C)OC(=O)N1CCN(Cc2cn(nn2)[C@H]2C[C@H](N(C2)C(=O)CCCc2ccccc2)C(=O)N2CCCC2)CC1 |r| Show InChI InChI=1S/C31H45N7O4/c1-31(2,3)42-30(41)36-18-16-34(17-19-36)21-25-22-38(33-32-25)26-20-27(29(40)35-14-7-8-15-35)37(23-26)28(39)13-9-12-24-10-5-4-6-11-24/h4-6,10-11,22,26-27H,7-9,12-21,23H2,1-3H3/t26-,27-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mi...				J Med Chem 55: 9856-67 (2012) Article DOI: 10.1021/jm301060g BindingDB Entry DOI: 10.7270/Q2SN0B3S
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50399723 (CHEMBL2178974) Show SMILES CC(C)(C)OC(=O)N1CCN(Cc2cn(nn2)[C@H]2C[C@H](N(C2)C(=O)CCCc2ccccc2)C(=O)N2CCCC2)CC1 |r| Show InChI InChI=1S/C31H45N7O4/c1-31(2,3)42-30(41)36-18-16-34(17-19-36)21-25-22-38(33-32-25)26-20-27(29(40)35-14-7-8-15-35)37(23-26)28(39)13-9-12-24-10-5-4-6-11-24/h4-6,10-11,22,26-27H,7-9,12-21,23H2,1-3H3/t26-,27-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of human seminal plasma DPP2 assessed as pNA release from Lys-Ala-p-nitroanilide substrate pre-incubated with enzyme for 15 min prior to s...				J Med Chem 55: 9856-67 (2012) Article DOI: 10.1021/jm301060g BindingDB Entry DOI: 10.7270/Q2SN0B3S
					More data for this Ligand-Target Pair