BDBM50400198 CHEMBL572368

SMILES: CC(Cc1ccccc1)(C(=O)NO)C(=O)NCc1ccc(F)cc1

InChI Key: InChIKey=MTWFVXDQVQRQQS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50400198   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aminopeptidase N (Sus scrofa (Pig))	BDBM50400198 (CHEMBL572368) Show SMILES CC(Cc1ccccc1)(C(=O)NO)C(=O)NCc1ccc(F)cc1 Show InChI InChI=1S/C18H19FN2O3/c1-18(17(23)21-24,11-13-5-3-2-4-6-13)16(22)20-12-14-7-9-15(19)10-8-14/h2-10,24H,11-12H2,1H3,(H,20,22)(H,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of porcine kidney microsomal neutral aminopeptidase using Leu-pNA as substrate preincubated for 10 mins				J Med Chem 55: 10909-17 (2012) Article DOI: 10.1021/jm301506h BindingDB Entry DOI: 10.7270/Q2Z60Q6R
					More data for this Ligand-Target Pair