BindingDB logo
myBDB logout

null

SMILES: COc1ccc(cn1)-c1cc(cnc1N)-c1ccc(cc1)S(=O)(=O)N(C)C

InChI Key: InChIKey=NTBMDNFTKNXWSC-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50400224   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))		BDBM50400224
PNG
(CHEMBL2181492)
Show SMILES COc1ccc(cn1)-c1cc(cnc1N)-c1ccc(cc1)S(=O)(=O)N(C)C
Show InChI InChI=1S/C19H20N4O3S/c1-23(2)27(24,25)16-7-4-13(5-8-16)15-10-17(19(20)22-12-15)14-6-9-18(26-3)21-11-14/h4-12H,1-3H3,(H2,20,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 9.70E+3n/an/an/an/an/an/a



University of Cape Town

Curated by ChEMBL


Assay Description
Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assay

J Med Chem 55: 11022-30 (2012)


Article DOI: 10.1021/jm301476b
BindingDB Entry DOI: 10.7270/Q2F76DQQ
More data for this
Ligand-Target Pair