BDBM50400786 CHEMBL4171037

SMILES: Cl.Cl.CC(=N)NCc1cccc(CNC(=O)[C@@H](N)CCC(N)=O)c1

InChI Key: InChIKey=AMPBKBPXEOLWSW-GXKRWWSZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50400786   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50400786 (CHEMBL4171037) Show SMILES Cl.Cl.CC(=N)NCc1cccc(CNC(=O)[C@@H](N)CCC(N)=O)c1 |r| Show InChI InChI=1S/C15H23N5O2.2ClH/c1-10(16)19-8-11-3-2-4-12(7-11)9-20-15(22)13(17)5-6-14(18)21;;/h2-4,7,13H,5-6,8-9,17H2,1H3,(H2,16,19)(H2,18,21)(H,20,22);2*1H/t13-;;/m0../s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Chieti "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...				Eur J Med Chem 152: 53-64 (2018) Article DOI: 10.1016/j.ejmech.2018.04.027 BindingDB Entry DOI: 10.7270/Q2C2500M
					More data for this Ligand-Target Pair