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SMILES: CCc1c(nc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3CC#N)cc12)-c1cnccc1C

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 504008   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human))	BDBM504008 ((1R,2S)—N-[8-amino-5-ethyl-6-(4-methylpyridin...) Show SMILES CCc1c(nc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3CC#N)cc12)-c1cnccc1C |r| Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.139	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Lanth: For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. Th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CV4MW8
					More data for this Ligand-Target Pair