BDBM50402493 CHEMBL2204048

SMILES: Clc1ccc(Cc2c([nH]c(=O)[nH]c2=O)[C@@H]2CC[C@@H](CC2)c2ccccc2)c(Cl)c1

InChI Key: InChIKey=XKNKJFGPZIVCTA-IYBDPMFKSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50402493   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50402493 (CHEMBL2204048) Show SMILES Clc1ccc(Cc2c([nH]c(=O)[nH]c2=O)[C@@H]2CC[C@@H](CC2)c2ccccc2)c(Cl)c1 |r,wU:14.14,17.21,(64.01,-42.17,;64,-43.7,;62.65,-44.46,;62.65,-46,;63.98,-46.79,;63.98,-48.35,;62.65,-49.13,;62.65,-50.69,;61.31,-51.45,;59.97,-50.69,;58.62,-51.48,;59.97,-49.14,;61.32,-48.37,;61.32,-46.83,;63.96,-51.46,;63.96,-53,;65.27,-53.77,;66.61,-53.01,;66.61,-51.47,;65.29,-50.69,;67.94,-53.79,;69.27,-53.03,;70.59,-53.8,;70.59,-55.35,;69.25,-56.11,;67.94,-55.33,;65.34,-46.03,;66.67,-46.81,;65.34,-44.49,)| Show InChI InChI=1S/C23H22Cl2N2O2/c24-18-11-10-17(20(25)13-18)12-19-21(26-23(29)27-22(19)28)16-8-6-15(7-9-16)14-4-2-1-3-5-14/h1-5,10-11,13,15-16H,6-9,12H2,(H2,26,27,28,29)/t15-,16+	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human recombinant glucocorticoid receptor expressed in baculovirus after 18 hrs by scintillation counting anal...				Bioorg Med Chem Lett 22: 7376-80 (2012) Article DOI: 10.1016/j.bmcl.2012.10.074 BindingDB Entry DOI: 10.7270/Q26111GW
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50402493 (CHEMBL2204048) Show SMILES Clc1ccc(Cc2c([nH]c(=O)[nH]c2=O)[C@@H]2CC[C@@H](CC2)c2ccccc2)c(Cl)c1 |r,wU:14.14,17.21,(64.01,-42.17,;64,-43.7,;62.65,-44.46,;62.65,-46,;63.98,-46.79,;63.98,-48.35,;62.65,-49.13,;62.65,-50.69,;61.31,-51.45,;59.97,-50.69,;58.62,-51.48,;59.97,-49.14,;61.32,-48.37,;61.32,-46.83,;63.96,-51.46,;63.96,-53,;65.27,-53.77,;66.61,-53.01,;66.61,-51.47,;65.29,-50.69,;67.94,-53.79,;69.27,-53.03,;70.59,-53.8,;70.59,-55.35,;69.25,-56.11,;67.94,-55.33,;65.34,-46.03,;66.67,-46.81,;65.34,-44.49,)| Show InChI InChI=1S/C23H22Cl2N2O2/c24-18-11-10-17(20(25)13-18)12-19-21(26-23(29)27-22(19)28)16-8-6-15(7-9-16)14-4-2-1-3-5-14/h1-5,10-11,13,15-16H,6-9,12H2,(H2,26,27,28,29)/t15-,16+	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor in human SW1353 cells assessed as inhibition of dexamethasone-induced luciferase expression after 16 h...				Bioorg Med Chem Lett 22: 7376-80 (2012) Article DOI: 10.1016/j.bmcl.2012.10.074 BindingDB Entry DOI: 10.7270/Q26111GW
					More data for this Ligand-Target Pair