null

SMILES: O[C@@H](CNC1CCN(Cc2ccc(Cl)c(Cl)c2)CC1)COc1ccc2ncsc2c1

InChI Key: InChIKey=MNXRFTOYSSFEST-KRWDZBQOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50402810   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50402810 (CHEMBL2208418) Show SMILES O[C@@H](CNC1CCN(Cc2ccc(Cl)c(Cl)c2)CC1)COc1ccc2ncsc2c1 |r| Show InChI InChI=1S/C22H25Cl2N3O2S/c23-19-3-1-15(9-20(19)24)12-27-7-5-16(6-8-27)25-11-17(28)13-29-18-2-4-21-22(10-18)30-14-26-21/h1-4,9-10,14,16-17,25,28H,5-8,11-13H2/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4- (methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK...				Bioorg Med Chem Lett 22: 7702-6 (2012) Article DOI: 10.1016/j.bmcl.2012.09.113 BindingDB Entry DOI: 10.7270/Q2CJ8FNG
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50402810 (CHEMBL2208418) Show SMILES O[C@@H](CNC1CCN(Cc2ccc(Cl)c(Cl)c2)CC1)COc1ccc2ncsc2c1 |r| Show InChI InChI=1S/C22H25Cl2N3O2S/c23-19-3-1-15(9-20(19)24)12-27-7-5-16(6-8-27)25-11-17(28)13-29-18-2-4-21-22(10-18)30-14-26-21/h1-4,9-10,14,16-17,25,28H,5-8,11-13H2/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]-pyrilamine from human histamine H1 receptor expressed in recombinant CHOK1 cells after 1 hr				Bioorg Med Chem Lett 22: 7702-6 (2012) Article DOI: 10.1016/j.bmcl.2012.09.113 BindingDB Entry DOI: 10.7270/Q2CJ8FNG
					More data for this Ligand-Target Pair