null

SMILES: CS(=O)(=O)c1ccccc1C(=O)NC[C@@H](O)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=JMGBVGDZPLNFAE-OAHLLOKOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50402811   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50402811 (CHEMBL2208428) Show SMILES CS(=O)(=O)c1ccccc1C(=O)NC[C@@H](O)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C22H26Cl2N2O5S/c1-32(29,30)21-5-3-2-4-18(21)22(28)25-13-15(27)14-26-10-8-16(9-11-26)31-17-6-7-19(23)20(24)12-17/h2-7,12,15-16,27H,8-11,13-14H2,1H3,(H,25,28)/t15-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	15.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4- (methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK...				Bioorg Med Chem Lett 22: 7702-6 (2012) Article DOI: 10.1016/j.bmcl.2012.09.113 BindingDB Entry DOI: 10.7270/Q2CJ8FNG
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50402811 (CHEMBL2208428) Show SMILES CS(=O)(=O)c1ccccc1C(=O)NC[C@@H](O)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C22H26Cl2N2O5S/c1-32(29,30)21-5-3-2-4-18(21)22(28)25-13-15(27)14-26-10-8-16(9-11-26)31-17-6-7-19(23)20(24)12-17/h2-7,12,15-16,27H,8-11,13-14H2,1H3,(H,25,28)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]-pyrilamine from human histamine H1 receptor expressed in recombinant CHOK1 cells after 1 hr				Bioorg Med Chem Lett 22: 7702-6 (2012) Article DOI: 10.1016/j.bmcl.2012.09.113 BindingDB Entry DOI: 10.7270/Q2CJ8FNG
					More data for this Ligand-Target Pair