Found 6 hits for monomerid = 50402857 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50402857
(CHEMBL2205593)Show SMILES Fc1cccc(c1C(=O)Nc1sc2COCCc2c1C(=O)N1CC(F)(F)C1)C(F)(F)F Show InChI InChI=1S/C19H14F6N2O3S/c20-11-3-1-2-10(19(23,24)25)14(11)15(28)26-16-13(9-4-5-30-6-12(9)31-16)17(29)27-7-18(21,22)8-27/h1-3H,4-8H2,(H,26,28) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 444 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nycomed Pharma Pvt. Ltd
Curated by ChEMBL
| Assay Description Displacement of [3H]-CP55,940 from human CB2 receptor after 60 mins by microscintillation counting analysis |
Bioorg Med Chem Lett 22: 7314-21 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.087 BindingDB Entry DOI: 10.7270/Q2QR4Z9V |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 2
(Rattus norvegicus (Rat)) | BDBM50402857
(CHEMBL2205593)Show SMILES Fc1cccc(c1C(=O)Nc1sc2COCCc2c1C(=O)N1CC(F)(F)C1)C(F)(F)F Show InChI InChI=1S/C19H14F6N2O3S/c20-11-3-1-2-10(19(23,24)25)14(11)15(28)26-16-13(9-4-5-30-6-12(9)31-16)17(29)27-7-18(21,22)8-27/h1-3H,4-8H2,(H,26,28) | KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 630 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nycomed Pharma Pvt. Ltd
Curated by ChEMBL
| Assay Description Displacement of [3H]-CP55,940 from rat CB2 receptor after 60 mins by microscintillation counting analysis |
Bioorg Med Chem Lett 22: 7314-21 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.087 BindingDB Entry DOI: 10.7270/Q2QR4Z9V |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50402857
(CHEMBL2205593)Show SMILES Fc1cccc(c1C(=O)Nc1sc2COCCc2c1C(=O)N1CC(F)(F)C1)C(F)(F)F Show InChI InChI=1S/C19H14F6N2O3S/c20-11-3-1-2-10(19(23,24)25)14(11)15(28)26-16-13(9-4-5-30-6-12(9)31-16)17(29)27-7-18(21,22)8-27/h1-3H,4-8H2,(H,26,28) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.11E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nycomed Pharma Pvt. Ltd
Curated by ChEMBL
| Assay Description Displacement of [3H]-CP55,940 from human CB1 receptor after 60 mins by microscintillation counting analysis |
Bioorg Med Chem Lett 22: 7314-21 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.087 BindingDB Entry DOI: 10.7270/Q2QR4Z9V |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Rattus norvegicus (rat)) | BDBM50402857
(CHEMBL2205593)Show SMILES Fc1cccc(c1C(=O)Nc1sc2COCCc2c1C(=O)N1CC(F)(F)C1)C(F)(F)F Show InChI InChI=1S/C19H14F6N2O3S/c20-11-3-1-2-10(19(23,24)25)14(11)15(28)26-16-13(9-4-5-30-6-12(9)31-16)17(29)27-7-18(21,22)8-27/h1-3H,4-8H2,(H,26,28) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nycomed Pharma Pvt. Ltd
Curated by ChEMBL
| Assay Description Displacement of [3H]-CP55,940 from rat CB1 receptor after 60 mins by microscintillation counting analysis |
Bioorg Med Chem Lett 22: 7314-21 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.087 BindingDB Entry DOI: 10.7270/Q2QR4Z9V |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50402857
(CHEMBL2205593)Show SMILES Fc1cccc(c1C(=O)Nc1sc2COCCc2c1C(=O)N1CC(F)(F)C1)C(F)(F)F Show InChI InChI=1S/C19H14F6N2O3S/c20-11-3-1-2-10(19(23,24)25)14(11)15(28)26-16-13(9-4-5-30-6-12(9)31-16)17(29)27-7-18(21,22)8-27/h1-3H,4-8H2,(H,26,28) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 798 | n/a | n/a | n/a | n/a |
Nycomed Pharma Pvt. Ltd
Curated by ChEMBL
| Assay Description Agonist activity at human CB1 receptor after 4 hrs by luciferase reporter gene assay |
Bioorg Med Chem Lett 22: 7314-21 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.087 BindingDB Entry DOI: 10.7270/Q2QR4Z9V |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50402857
(CHEMBL2205593)Show SMILES Fc1cccc(c1C(=O)Nc1sc2COCCc2c1C(=O)N1CC(F)(F)C1)C(F)(F)F Show InChI InChI=1S/C19H14F6N2O3S/c20-11-3-1-2-10(19(23,24)25)14(11)15(28)26-16-13(9-4-5-30-6-12(9)31-16)17(29)27-7-18(21,22)8-27/h1-3H,4-8H2,(H,26,28) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 6.5 | n/a | n/a | n/a | n/a |
Nycomed Pharma Pvt. Ltd
Curated by ChEMBL
| Assay Description Agonist activity at human CB2 receptor after 4 hrs by luciferase reporter gene assay |
Bioorg Med Chem Lett 22: 7314-21 (2012)
Article DOI: 10.1016/j.bmcl.2012.10.087 BindingDB Entry DOI: 10.7270/Q2QR4Z9V |
More data for this Ligand-Target Pair | |